Cannon Lab at the NOS

Jeff, Chris, and Ciara had a blast sharing our research at the 48th National Organic Chemistry Symposium at Notre Dame! It was great to meet new people, connect with old friends, and see a lot of inspirational chemistry over four days!

Photoredox-catalyzed Oxidation of Anions 

Our work on the photoredox-catalyzed oxidation of anions to generate electrophilic radicals is published in The Journal of Organic Chemistry! This work generates 1,3-dicarbonyl and amidyl radicals by a stepwise proton-coupled electron transfer process for the functionalization of alkenes. The result is a highly atom-economical process for hydro-, amido-, and dialkylation of alkenes. We used experimental and computational mechanistic experiments to understand the role of the catalyst as an electron shuttle between starting material and product molecules.

NIH Grant funded!

Our research in photoredox catalysis has been funded by a grant from the National Institute of General Medical Science of the National Institutes of Health! The funds from this grant will support a number of research students and any supplies they need to conduct their research. The reactions studied under this grant will enable the use of visible light to conduct challenging carbon-carbon bond forming reactions.