NIH Grant funded!

Our research in photoredox catalysis has been funded by a grant from the National Institute of General Medical Science of the National Institutes of Health! The funds from this grant will support a number of research students and any supplies they need to conduct their research. The reactions studied under this grant will enable the use of visible light to conduct challenging carbon-carbon bond forming reactions.

NSF Instrumentation Grant!

The chemistry department was just awarded a grant from the National Science Foundation to purchase a new nuclear magnetic resonance spectrometer! Thanks to Prof. Cannon as well as Profs. Despagnet-Ayoub, Hill, Navarro, and Udit for putting together a successful proposal. The features of this new instrument will advance our research and also allow us to include more hands-on NMR experience in the teaching lab.

Syntheses of Coniine, DAB-1, and Nectrisine

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Our work on the total syntheses of the alkaloid natural products (–)-coniine, DAB-1, and nectrisine just appeared in ACS Omega! This was collaborative work with Prof. Deardorff to develop a robust synthesis of these biologically active natural products. The approach utilizes an enzyme-catalyzed hydrocyanation to establish the key stereochemistry, which is followed by transition metal-catalyzed reactions to transform this building block into the natural products. We envision this approach as a general platform for the enantioselective syntheses of alkaloid natural products. Congrats to the undergraduates that worked on this project together!